Launching direct services in our 11th country of operation, Nigeria

m2m launched direct services in Nigeria in July—bringing our countries of operation to 11, including two now in West Africa. Our team of 45 Mentor Mothers started delivering services in 26 sites located around the country’s capital, Abuja, with a focus on integrated primary health care services for children living with, or exposed to, HIV as well as their caregivers. Additionally, m2m is working with government agencies and other stakeholders to help build a more robust and sustainable health system. Nigeria faces significant public health challenges—including a 23% mother-to-child HIV transmission rate in 20232 and maternal and child mortality rates that are among the highest in the world. We’re excited to say sannu (hello) to Nigeria and begin making a difference in this vibrant country.

Expanding our reach in two countries, including securing our largest-ever award 

m2m Lesotho was selected as the lead implementing partner for Bokamoso—a five-year, country-wide project funded by the United States Agency for International Development (USAID), m2m’s largest-ever award. In its first year, Bokamoso aims to improve the health and well-being of approximately 80,900 orphans and vulnerable children, adolescent girls, and young women, with a team of 500 frontline staff.

m2m also expanded our reach in Zambia with a five-year project—the USAID Zambia Integrated Health (ZIH) Activity—implemented by a consortium of partners led by Pact. As a key partner, m2m is delivering integrated primary health care services designed to end HIV and reduce preventable deaths. We are also helping to strengthen Zambia’s health system by providing technical assistance.

We built on our integration of tuberculosis (TB) services into our work

m2m continued to expand our scope beyond HIV this year, in line with our strategic goal to provide integrated primary health care services to both end HIV and tackle life-threatening health issues that disproportionately affect those living with HIV. That included expanding our work on TB—the main cause of death among people living with HIV—with our first-ever TB-focused programme to improve awareness, testing, and treatment of TB in South Africa.  

In South Africa, we teamed up with The Aurum Institute for a five-year USAID-funded initiative called Accelerate TB Elimination and Program Resilience Activity (ACCELERATE 1). m2m has trained and deployed 90 health workers called Community Peer Mentors (CPMs) and 10 Community Coordinators at 69 health facilities and surrounding communities in Gauteng and Kwazulu-Natal Provinces. These CPMs offer education and health services designed to identify, prevent, diagnose, and treat TB.

We also integrated TB services into our work in Lesotho and Uganda

Thanks to a new partnership with GSK plc, we are also integrating TB services into our work in Lesotho and Uganda. Through this partnership—initially lasting 12 months—we are aiming to reach over 40,000 people with TB services, integrated into our core programme by upskilling and supporting our frontline teams. Through this partnership, we hope to help achieve global targets on TB including increasing the proportion of people screened and tested for TB and initiated onto TB-preventative treatment.

Our cervical cancer work made headlines

“I wish there was someone like me when I was their age. Someone I could ask questions and talk to about my health,” shared Jessie Mzemba, m2m Mentor Mother from Malawi, in a powerful interview. m2m was proud to see our work promoting the uptake of human papillomavirus vaccine to prevent cervical cancer in Malawi featured in The Guardian earlier this year. With the risk of cervical cancer up to six times higher for women living with HIV, creating demand for the vaccine is critical in Malawi—which has among the highest rates of HIV and deaths from cervical cancer. That is why the work of m2m Peer Mentors like Jessie Mzemba is so important

Expanding Impact, Reaching More

In 2024, we saw strong growth across all key areas. The number of new clients increased by 48% (reaching a total 824,137 women, children, and families), we expanded into a new country, and both our service sites and frontline teams grew significantly. This progress was driven by expanding our programmes, securing major multi-year funding, and introducing new services—especially in Zambia, Lesotho, and Nigeria.

Remaining committed to creating an HIV-free generation

For more than 20 years, m2m has built a peer-led programme to prevent and end mother-to-child transmission (PMTCT) of HIV. In 2024, we continued to deliver on this promise, achieving a PMTCT rate of 0.6% among our enrolled clients. While this is a slight increase on previous years (including on 2023 when we achieved the incredible milestone of a 0% PMTCT rate among m2m clients), the 2024 data remains far below the global benchmark of 5%3 and continues to reflect the strength of our model. These results also show that virtual elimination of mother-to-child transmission is achievable when prevention, adherence support, and follow-up services are underpinned by a strong community-based approach.

Ending mother-to-child HIV transmission is not just a goal—it can be done.

Continuing to deliver against UNAIDS 95-95-95 targets to end HIV

In 2024, we delivered strong results across our client cohort. We met or exceeded UNAIDS’ 95-95-95 targets4—except for the first 95 on HIV testing, where 92% of our clients knew their status—while maintaining high viral suppression, ensuring infants were tested and followed up, and keeping clients engaged in care. These results were made possible by our skilled community health workers, strong partnerships with health facilities, trusted relationships within communities, and close monitoring of each client.

Expanding the delivery of our integrated primary health care services

In 2024, m2m expanded our primary health care services beyond HIV to include tuberculosis (TB), malaria, family planning, early childhood development, and broader maternal and child health priorities. By building on our trusted peer-led HIV platform, we ensured women and families could access coordinated, comprehensive care through a single delivery model across multiple countries.

Our impact was significant: over 162,000 clients were screened for TB in Lesotho, South Africa, and Uganda, with 96% of those diagnosed starting treatment. In Uganda, more than 74,000 people received malaria education, and over 12,800 were treated. Cervical cancer screening in Malawi reached nearly 67,000 women, with over 2,000 screened and 17 treated. These results show how integrating essential services into routine primary care improves health outcomes for women, children, and families.

All data in the section above is from our 2024 Annual Programme Review.5

The 79th United Nations General Assembly week

m2m made our presence known at two major global events this year. During the 79th United Nations General Assembly week in New York City in September, Bupe Sinkala—m2m Spokeswoman and community health worker (CHW) from Zambia—made a powerful case for more paid and professional CHWs. Her remarks reached policy, government, and business leaders at events hosted by USAID, the World Bank, Africa CDC, Johnson & Johnson, and the Business Council for International Understanding. We also hosted an event at Goals House with Cartier Philanthropy on how to deliver real change for girls and young women by focusing on community-based solutions that work. Bupe was joined by a group of esteemed panelists from the Wellbeing Foundation Africa, IDInsight, and the Obama Foundation.

The 2024 International AIDS Conference

m2m was also out in full force at the 2024 International AIDS Conference in Munich, Germany, in July—amplifying frontline voices; challenging stereotypes through art; and speaking in multiple sessions. We also hosted a satellite session, Radical Honesty and Bold Solutions to End AIDS, with support from Gilead Sciences, Inc., moderated by Christine Stegling, Deputy Executive Director at UNAIDS. The key takeaway: Building a more inclusive, innovative, and compassionate global HIV response by putting people first is essential. m2m Lesotho Country Director, Mpolokeng Mohloai, said it best: “There’s no such thing as hard-to-reach people… only hard-to-get services.”  

The Power of Mother at The Mothers' Ball

In November, The Mothers’ Ball returned to the iconic V&A South Kensington in London, delivering another unforgettable celebration of the Power of Mothers and the vibrancy of the African continent. The event was hosted by Team Great Britain Olympian Perri Shakes-Drayton, and featured performances by Natalie Rushdie, The Zulu Stomp, ELIZA, and Cuppy. Guests heard the inspiring stories of three m2m clients and the woman who transformed each of their lives: m2m Mentor Mother Bupe Sinkala from Zambia, who was in London for the event. The evening was a poignant testament to the power of women to change lives.

New partnerships to strengthen health systems

As well as serving our clients directly, we strengthen health systems by advising governments and key partners. Among the highlights: We were proud to be invited by the Africa Centres for Disease Control and Prevention to serve on the Continental Coordination Mechanism for CHWs, with a mandate to advise on the development of policy, guidelines, and standard operating procedures for initiatives across African Union (AU) member states. This is in support of the AU’s target of deploying two million more CHWs by 2030. We also partnered with national and sub-national governments in six countries to strengthen health systems in key service areas, including HIV, maternal health, and immunisation.

Here are two illustrative examples:

• In Lesotho, we helped to cost a national plan for PMTCT of HIV, shaped a new national TB Acceleration Plan, and attended a regional conference on antenatal care in Kenya as part of the Lesotho government delegation to share our learnings.

• In Malawi, we engaged with the Ministry of Health and other partners on the topic of preventing seroconversion of HIV-exposed children during the breastfeeding period. We shared our strategies to ensure mothers living with HIV adhere to their treatments, and that mothers who are HIV-free remain that way. We also continued to assist with the rollout and monitoring of the National Community Health Framework 2022-2030 (launched in 2023), which we played an important role in shaping, along with other members of the Community Health Impact Coalition.

DONORS

m2m is built on partnerships. That includes the trusted partnerships that m2m Mentor Mothers form with their clients, health centre staff, and communities. Equally important are the partnerships with new and longstanding donors and supporters that drive our work and enable us to continue to expand in scale, scope, and impact. We are incredibly grateful for all of these partnerships and know what a profound role they have played in making us the organisation we are today.

 To see our 2024 donors, click here.

BOARD

In each African country where we deliver health services, m2m is locally registered. At a global level, the m2m family is made up of three separate legal entities—mothers2mothers South Africa, mothers2mothers (U.K.) Limited, and mothers2mothers United States.  Each of these entities is committed to our shared mission and governed by a set of independent Board of Directors/Trustees. Our Directors/Trustees are a diverse group of individuals committed to ensuring health and opportunity for all.  

 * Non-voting member   

South African Board of Directors

from left to right

Jolly Mokorisi
Chair, m2mSA 
Owner, Mokorisi Financial Consulting  

Frank Beadle de Palomo * 
President & Chief Executive Officer, m2m  

Dr. Mitch Besser   
Founder, m2m  

Dr. Lynette Ann Denny  
(passed away June 2024)
Professor, Department of Obstetrics & Gynaecology, University of Cape Town    

Dr. Samukeliso Dube  
Executive Director, FP2030

Nkanyiso Hlongwa
Partner, Bridgespan

Tom Kagerer *  
m2mSA Board Observer  
Board Advisor, LGT Philanthropy

Derek Lubner  
Chair and Co-Founder, Izinga Assist

Musa Makhunga 
(stepped down May 2024)
Managing Director, HR Matters Holdings   

Mpumi Nkabinde
Independent Capital Consultant

Chad D. Rathner   
Secretary, m2mSA  
Chief Operating Officer, m2m
   

Boitumelo Semete-Makokotleta 
Chief Executive Officer, SAPHRA, South African Health Products Regulatory Authority

Dr. Tim Tucker 
Chief Executive Officer, SEAD (PTY) Ltd

United Kingdom Board of Trustees

from left to right

Afua Basoah  
Chair, m2mUK 
Health & Social Impact Strategist, HealthTech

Andrea Hartley  
Vice Chair, m2mUK
Founder and CEO, Skating Panda 

Souleymane Ba 
(stepped down February 2025)
Partner, LeapFrog Investments

Frank Beadle de Palomo * 
President & Chief Executive Officer, m2m  

Dr. Annemiek de Ruiter
VP & Head of Global Sciences, ViiV Healthcare

Dr. Tim Evans  
Medical Doctor

Peggy Grueninger Schlapfer
(stepped down December 2024)
Head of Corporate Donations and Philanthropy,  
F. Hoffmann-La Roche Ltd

Keith Kibirango  
(stepped down December 2024)
Chief Executive Officer, NGM Consulting (New Global Markets)

Derek Lubner  
Chair and Co-Founder, Izinga Assist  

Charles McGregor  
Trustee, University of Cape Town Trust  

Naomi Walkland
Chief Marketing Officer, Motorway

United States Board of Directors

from left to right

Colin Freund  
Chair, m2mUS 
Advisor

Meena Ravella  
Vice-Chair, m2mUS
Advisor & Consultant  

Laura Bartlett  
(term ended February 2024)
Retired Executive

Frank Beadle de Palomo * 
President & Chief Executive Officer, m2m  

Dr. Mitch Besser  
Founder, m2m 

Leslie Brunner
(term ended February 2024)
Chief People Officer, Devoted Health   

Katy Digovich 
(stepped down August 2024)
Chief Executive Officer, Minutia  

Colleen Hancock  
(stepped down April 2025)
Advisor & Mentor  

Loretta Kelly  
Director of Strategic Marketing, Blue Diamond Growers

Ariel Knowles  
Finance Professional & Consultant   

Karin Norington-Reaves  
Consultant

Modupe Odusote  
(term ended February 2024)
Human Resources Consultant

Neena Patil
Chief Legal Officer, Snr VP, Legal & Corporate Affairs, Jazz Pharmaceuticals

Terry Peigh  
Snr VP & Managing Director, Interpublic Group of Companies

Kate Schachern  
(stepped down April 2025)
Communications, Management & Operations Leader

Robin Smalley  
Co-Founder, m2m

Officers of the Corporation  

from left to right

Chad D. Rathner  
Secretary, m2mSA  
Chief Operating Officer, m2m  

Sarah Sheldon  
Secretary, m2mUS  
Head of Risk & Compliance, Operations, m2m 

2024 FINANCIALS

In 2024, mothers2mothers maintained a strong and stable financial position while continuing to deliver high-impact programmes across our country platforms. Geopolitical shifts, competing humanitarian priorities, and constrained donor budgets continued to influence development funding flows across the sector.

Total revenue and support for the year amounted to $24.2 million, compared with $25.8 million in 2023. The decrease reflects the planned completion of several government-funded awards and cooperation agreements, as well as currency volatility during the year rather than a reduction in programmatic demand or performance.

Despite these pressures, we maintained strong cost discipline, investing 80% of total expenditure directly in programmes supporting the communities we serve. This reflects our continued focus on directing resources toward frontline service delivery and measurable impact.  

We remain deeply grateful for the continued partnership of the United States Government through U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), USAID, and Centers for Disease Control and Prevention (CDC), whose support continues to underpin much of our work. We also value the sustained commitment of philanthropic partners including Cartier Philanthropy, LGT Venture Philanthropy, and Jasmine Social Investments. 

The organisation recorded a planned deficit in 2024, reflecting both the timing of grant income and a deliberate, Board-approved drawdown from investment reserves to support operations and strategic priorities.

As a result, reserves declined during the year; however, the organisation remains financially strong, ending the year with reserves of $36.3 million, including $30.5 million in unrestricted funds. These reserves provide a strong foundation to support ongoing operations and future growth.

With strong reserves, trusted partners and a clear strategic direction, we are well positioned to navigate a shifting funding environment while continuing to deliver measurable impact at scale.

CONTACT US

Global HQ: mothers2mothers South Africa
33 Martin Hammerschlag Way, 5th Floor, Foreshore
Cape Town, South Africa 8001
office: +27 (0)21 466 9160
contact: [email protected]

Europe: mothers2mothers U.K.
office: +44 (0) 203 867 7120 
contact: [email protected]

North America: mothers2mothers U.S.
office: +1 323 312 3450
contact: [email protected]

To engage with us or support us, please contact:
Tricia Cassidy 
Senior Director: Resource Development 
[email protected] 

Shanaaz Ebrahim
Senior Communications Lead
[email protected] 

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References

1. https://esaro.unfpa.org/en/news/time-now-ending-leading-cause-maternal-death

2. https://www.unaids.org/en/regionscountries/countries/nigeria

 3. https://www.who.int/initiatives/triple-elimination-initiative-of-mother-to-child-transmission-of-hiv-syphilis-and-hepatitis-b/validation/path

4. https://www.unaids.org/sites/default/files/media_asset/progress-towards-95-95-95_en.pdf

5. Disclaimer: mothers2mothers (m2m) strives to provide accurate performance data. Our data quality and routine monitoring and evaluation systems are regularly reviewed and updated. We benchmark and validate internal data through external evaluations and data quality assurance processes. National and site comparisons often rely on public domain data; m2m has no control over the quality of such data. As m2m tracks mother-baby pairs, each pregnancy is catalogued as a new client in our PMTCT programme, potentially cumulatively leading to a higher count for adult women clients.